On breezy autumn evenings, nothing compares to a comforting homemade dish loaded with savory flavors and a touch of nostalgia. This meatloaf and stuffing casserole combines two timeless classics into one delightful meal that’s a hit for any gathering or a cozy family dinner. Its rich tastes and hearty texture make it a beloved choice, ensuring it’s a recipe you’ll return to repeatedly. Discover the melding of herbs, spices, and the golden, crusty topping within your first bite, and allow this recipe to become a new favorite in your culinary repertoire.
Growing up, Sundays at our house meant one thing: the comforting aroma of something delicious baking in the oven. My grandmother was the maestro behind many of our family’s favorite dishes, and this Casserole Recipe was always a star player. Each layer of the dish tells a story of family, tradition, and love. I remember sneaking small tastes while it cooled, each forkful a warm hug on my taste buds. Now, I’ve adapted this nostalgic recipe to fit today’s tastes while preserving all that charming, home-cooked goodness my grandmother taught me to cherish.
Why You’ll Love This Recipe
This dish is a blend of familiarity and comfort, perfect for those seeking a taste of home. The unique combination of meatloaf and stuffing ensures a meal that balances hearty meatiness with a delightful medley of herbs and bread. This recipe is straightforward, allowing busy cooks to prepare it with ease while promising impressive results every time. Additionally, its versatility in serving options—from elegant dinners to casual family meals—makes it an ideal choice for various occasions.
Ingredients Notes
To ensure the ultimate experience of flavors and textures, let’s explore the key ingredients you’ll need. Ground Beef forms the base of the meatloaf, and combining it with breadcrumbs gives just the right amount of density. Choose high-fat content meat for extra juiciness. The classic stuffing mix is enhanced with fresh herbs like sage and thyme, adding that earthy, aromatic essence. For a rich, binding component, eggs are crucial. Substitute with ground turkey for a lighter version or gluten-free breadcrumbs for dietary requirements.
Recipe Steps
Step 1
Preheat your oven to 375°F (190°C). Prepare a 9×13-inch baking dish by greasing it lightly with butter or non-stick spray. In a large mixing bowl, combine the Ground Beef, breadcrumbs, chopped onions, minced garlic, and a beaten egg. Season with salt, pepper, and a hint of smoked paprika for added warmth. Mix until just combined, being careful to not overwork the mixture, as this keeps the meatloaf tender.
Step 2
Press the meatloaf mixture into the prepared baking dish, forming an even layer. Bake it uncovered for about 15–20 minutes until it begins to crisp around the edges but stays moist within. Remove from the oven and let it rest while you prepare the stuffing layer. Meanwhile, reduce the oven temperature to 350°F (175°C).
Step 3
To make the stuffing, bring chicken or vegetable broth to a boil. Remove from heat, and stir in the stuffing mix along with the chopped celery and sautéed mushrooms, which provide earthy undertones. Optional: toss in a handful of dried cranberries for a sweet contrast. Allow the stuffing to sit and absorb the liquid until it’s tender and fluffy.
Step 4
Layer the prepared stuffing over the semi-cooked meatloaf in the baking dish. Press down lightly to ensure even coverage. Optionally, sprinkle grated Parmesan or shredded mozzarella for an indulgent cheesy topping that turns golden upon baking. Cover the dish with aluminum foil to prevent excessive browning.
Step 5
Bake the assembled casserole at 350°F (175°C) for another 25–30 minutes. The top layer should be golden and slightly crispy, releasing tantalizing aromas. Remove the foil during the last 5 minutes of baking if a crispier topping is desired. Allow the casserole to cool for about 10 minutes before slicing. This resting phase helps each piece hold its shape upon serving.
Storage Options
Leftovers of this meatloaf and stuffing casserole can be stored in airtight containers, in the refrigerator, for up to four days. For extended storage, wrap the casserole tightly in plastic wrap followed by a layer of foil and freeze for up to three months. To reheat, allow it to thaw in the refrigerator overnight and then bake it at 350°F (175°C) for about 20 minutes until heated through.
Variations & Substitutions
Feel free to experiment with different proteins such as ground turkey or pork for a flavor variation. Vegetarians can substitute meat with lentils or chickpeas, and use vegetable broth for the stuffing. For a more Mediterranean twist, incorporate olives and sun-dried tomatoes into the stuffing mix, swapping traditional herbs with rosemary and oregano for a vibrant twist.
Serving Suggestions
This casserole is a robust entreé on its own but pairs wonderfully with a simple arugula salad drizzled with balsamic vinaigrette, offering a fresh counterbalance to the rich, savory flavors. It’s fitting for holiday family meals or weekend potlucks, presenting a comforting and crowd-pleasing option that is both filling and flavorful.
Frequently Asked Questions
Can I prepare this dish ahead of time? Absolutely! Prepare both the meatloaf and stuffing layers separately ahead of time. Once each component is cooked, layer them in the baking dish, cover tightly with foil, and refrigerate overnight. When ready to bake, remove from the fridge 30 minutes prior to baking to bring it to room temperature for even cooking.
What is the secret to an extra moist meatloaf? Using ingredients such as high-fat Ground Beef, eggs, and breadcrumbs helps bind the mixture and retain moisture. Avoid over-mixing, as this can compact the meat, making it dense and dry. If you prefer a tangy kick, add a tablespoon of Worcestershire sauce or ketchup to the ground beef mix for added moisture and flavor.
How do I make a gluten-free version? Simply substitute the breadcrumbs with gluten-free breadcrumbs or crushed cornflakes for the meatloaf. For the stuffing, use your favorite gluten-free stuffing mix or toasted gluten-free bread pieces. Confirm that other ingredients, like broths and seasonings, are certified gluten-free as needed.
Experience the warmth and nostalgia of this meatloaf and stuffing casserole, a dish that promises to impress every diner with its savory flavors and comforting composition. Whether serving family or guests, this recipe stands out as a favorite in any home cook’s collection. Don’t hesitate to share this delicious comfort food with those you love, creating new memories around the table.

Meatloaf and Stuffing Casserole
Ingredients
Main Ingredients
- 2 lb ground beef preferably 80% lean
- 1 cup stuffing mix store-bought
- 1 pc egg beaten
- 1 cup milk any type
- 1 tbsp ketchup for topping
Instructions
Preparation Steps
- Preheat oven to 350°F (175°C).
- In a large bowl, combine ground beef, stuffing mix, beaten egg, and milk. Mix until just combined.
- Press the mixture into a greased baking dish.
- Spread ketchup over the top of the meatloaf mixture.
- Bake for 60 minutes or until the meat is fully cooked.