If you’re searching for a mouth-watering and simple-to-make family meal, this meatball sub Grilled Cheese casserole might just become your new favorite dish. This recipe brilliantly combines beloved flavors of hearty meatballs, tangy marinara sauce, and rich melted cheese — all enveloped in crispy bread, making it irresistible and inherently satisfying. Using simple ingredients, this dish quickly becomes a household staple that pleases everyone gathered around the dinner table.
I remember the first time I decided to whip up this delightful casserole was during a busy midweek evening. With three hungry kids clamoring and time not on my side, I stumbled upon the idea of merging two family favorites: meatball subs and Grilled Cheese. It was like a culinary revelation! The skeptical glances quickly turned into smiles of approval and satisfied bellies, making this an unforgettable kitchen triumph.
Why You’ll Love This Recipe
This recipe stands out because of its simplicity and delectability. Here are a few reasons why you’ll love preparing this delectable meal:
- Easy Assembly: With minimal prep time and straightforward assembly, this casserole is perfect for a fuss-free family dinner.
- Kid-Friendly: Combining two children’s favorites — meatball subs and grilled cheese — is bound to be a hit on any table.
- Comfort Food: It’s the ultimate comfort food with layers of cheesy goodness, hearty meat, and flavorful sauce.
- Customizable: You can easily adjust the ingredients to suit your family’s taste or accommodate dietary restrictions.
- Great for Leftovers: It reheats beautifully, making it ideal for meal prep or enjoying as leftovers the next day.
Ingredients Notes
Gathering the right ingredients is key to achieving a flavorful dish. Here’s a look at what’s needed and how to maximize their potential:
- Meatballs: You can use store-bought or homemade meatballs. For a healthier version, opt for turkey or chicken meatballs.
- Marinara Sauce: Choose a high-quality store-bought sauce or make your own for added flavor depth.
- Bread: Day-old crusty bread works best as it soaks up the sauce without getting too soggy.
- Cheese: Combine mozzarella and cheddar for the ultimate melted gooey texture.
- Basil: Fresh basil adds a lovely fresh zing. Dried basil can work in a pinch, but fresh is always best for bold flavors.
Recipe Steps
Step 1
Preheat your oven to 350°F (175°C). Begin by preparing the meatballs. Whether you’re making them from scratch or using pre-cooked ones, ensure they’re size-appropriate for bite-sized delight. Homemade meatballs can be seasoned with garlic, onion, and Italian herbs for added flavor.
Step 2
Pour a layer of marinara sauce at the bottom of your baking dish. Layer it with pieces of Crusty Bread personally diced to fit the pan and cover any sauce gaps. This bread layer acts as the base for soaking up the delicious flavors.
Step 3
Place the cooked meatballs evenly across the bread layer. Scoop more marinara sauce to cover them well, ensuring every meatball is blanketed for extra moist and tender bites.
Step 4
Create a generous blanket of cheese by covering the pan with shredded mozzarella and cheddar, or your family’s preferred cheese combo. Sprinkle fresh basil over the top for contrast and aromatic depth.
Step 5
Bake the casserole for about 25-30 minutes, or until the cheese is bubbly and golden brown. Allow it to cool slightly before serving to ensure the layers hold together when you cut through them.
Storage Options
To store leftovers, ensure the casserole has cooled to room temperature. Place it in an airtight container and refrigerate for up to three days. For long-term storage, slice individual portions, wrap them in plastic wrap, and then aluminum foil before freezing. To reheat, thaw in the refrigerator, and warm it in the oven at 350°F until hot and bubbly.
Variations & Substitutions
Customize the recipe creatively to suit dietary needs or flavor preferences:
- Gluten-Free: Use gluten-free bread and check the marinara sauce label for gluten-free certification.
- Vegetarian: Substitute meatballs with vegetarian versions or mushrooms for a hearty plant-based option.
- Spicy Twist: Add pepper flakes or jalapeños for those who enjoy an extra kick.
- Cheese Swap: Experiment with provolone or Monterey Jack for different flavor profiles.
Serving Suggestions
This dish is incredibly versatile, making it perfect for various occasions. Serve it during a cozy family dinner, at a potluck, or for game day. Pair it with a fresh garden salad or steamed veggies to balance the rich meatball and cheese combination. A crisp white wine or a fizzy drink complements the dish beautifully.
Frequently Asked Questions
Can I make this casserole ahead of time?
Yes, you can assemble the casserole a day in advance. Cover and refrigerate it until you’re ready to bake. Allow a few extra minutes of cooking time as it will be cold from the fridge.
Is it possible to use a different type of cheese?
Absolutely, you can experiment with any melting cheese that your family enjoys. Provolone, Monterey Jack, or even Gouda can bring new flavor dimensions to this dish.
How can I prevent the bread from getting too soggy?
Opt for stale or day-old bread, which absorbs the marinara sauce well without turning into mush. Position the bread pieces tightly in the dish and avoid over-saturating with sauce.
This easy and comforting meal proves to be a dinner winner time and again. Its adaptability, wholesomeness, and robust flavors make it not just a mere family meal but a cherished gathering-centered experience. The next time you’re in search of comfort food, remember this delightful casserole and enjoy the smiles that follow every serving.

Meatball Sub Grilled Cheese Casserole
Ingredients
Main Ingredients
- 1 lb ground beef preferably 80% lean
- 1 cup bread crumbs Italian style
- 2 cups marinara sauce store-bought or homemade
- 8 slices Italian bread thick cut
- 4 cups shredded mozzarella cheese
Instructions
Preparation Steps
- Preheat the oven to 375°F (190°C).
- In a bowl, mix ground beef, bread crumbs, and a pinch of salt and pepper.
- Form mixture into 1-inch meatballs.
- In a pan over medium heat, brown the meatballs on all sides.
- Place the meatballs in a baking dish and cover with marinara sauce.
- Top with mozzarella cheese and arrange bread slices on top.
- Bake for 25-30 minutes, until cheese is bubbly and golden.