Grease and flour a 6-cup Bundt pan.
Reserve 2 tablespoons flour, then mix the remaining flour with the baking powder and salt.
Beat the orange zest, sugar, and butter until combined, then mix in the egg, orange extract, and vanilla extract.
Mix in half the flour mixture with the milk and lemon juice, then add the remaining flour mixture.
Toss the blueberries with the reserved flour and gently fold them into the batter.
Pour 1/2 cup water into the Instant Pot, add the trivet, fill the prepared pan with batter, and cover the pan with paper towel and foil.
Pressure cook on high for 50 minutes, then allow a 20-minute natural pressure release.
Uncover the bread, let condensation evaporate, transfer it to a serving plate, and cool completely.
Stir the orange juice with the powdered sugar and pour the glaze over the cooled bread.